Mechanism of immortalization
نویسندگان
چکیده
منابع مشابه
Protection from oxidative stress by enhanced glycolysis; a possible mechanism of cellular immortalization.
Reactive oxygen species (ROS) play a crucial role not only in the physiological signal transduction but also in the pathogenesis of several human diseases such as atherosclerosis, neuro-degenerative diseases, metabolic disorders, aging or cancer amongst others. Oxidative stress is also responsible for cellular and organism senescence, in accordance with what Harman initially proposed in the fre...
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ژورنال
عنوان ژورنال: AGE
سال: 1999
ISSN: 0161-9152,1574-4647
DOI: 10.1007/s11357-999-0008-1